Liver transplantation

Liver transplantation - technical

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Liver disease and the skin

Skin diseases - Liver disease and the skin - technical

Numerous systemic diseases may affect the liver and some of these will have cutaneous features (e.g. as occurs in sarcoidosis). The predominant dermatological features and dermatoses associated with liver diseases are discussed here. For a full discussion of liver disease, see: liver disease.

Alpha1-Antitrypsin deficiency and the serpinopathies

Alpha1-Antitrypsin deficiency is a rare genetic disorder in which a person is missing the enzyme alpha1-antitrypsin, which protects the body from damage by other enzymes. The disease mainly affects tissues in the lungs, resulting in emphysema, and the liver, causing cirrhosis. The effects of alpha1- antitrypsin deficiency may not become apparent until after the age of 30. There is no cure, but symptoms can be relieved by drug treatment. In severe cases, a liver transplant may be a possibility

Metabolic disorders - Alpha-1 Antitrypsin deficiency and the serpinopathies - technical

Liver diseases specific to pregnancy

Liver diseases specific to pregnancy - technical

Hyperemesis gravidarum

Although nausea and vomiting may occur in up to 75% of pregnancies, severe vomiting leading to dehydration, ketonuria, electrolyte disturbances, and nutritional deficiency is rare, developing in 2 to 16 of every 1000 pregnancies. Nutritional deficiency has been so severe as to progress to Wernicke’s encephalopathy and changes in serum sodium may precipitate osmotic demyelination (central pontine myelinolysis).