gastroenterology

Taking PPI Heartburn Medication May Increase Your Risk of Dying

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Proton pump inhibitor (PPI) medication may increase risk of death

New research suggests people on proton pump inhibitors are more likely to die than those taking different antacid or none at all.

Millions of people taking common heartburn and indigestion medications could be at an increased risk of death, research suggests.

The drugs, known as proton pump inhibitors (PPIs), reduce acid production by the stomach lining and are very widely prescribed, with low doses also available without prescription from pharmacies. In the UK, doctors issue more than 50m prescriptions for PPIs every year.

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The genetics of inherited cancers - Genetic predisposition to the common cancers

The genetics of inherited cancers - Genetic predisposition to the common cancers - technical

Breast cancer

Breast cancer is the most common noncutaneous cancer in women in the Western world. Several genes predispose to high risks of breast cancer, most notably BRCA1 and BRCA2 (breast cancer 1 and 2 genes) which were isolated in 1994 and 1995. These genes, when mutated, also predispose to ovarian cancer, and also have a small (<10%) risk of causing other cancers (e.g. pancreas, bile duct, melanoma, male breast cancer, prostate cancer).

Diverticular Disease

The presence of small protruding sacs or pouches called diverticula in the intestinal wall, and the symptoms or complications caused by them. The term diverticulosis signifies the presence of diverticula in the intestine. Diverticulitis is a complication produced by inflammation in one or more diverticula.

Diverticulitis

Inflammation of diverticula (abnormal pouches) in the wall of the intestine, particularly in the colon. Diverticulitis is a form of diverticular disease and a complication of diverticulosis.

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